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タイトル右室収縮時間に関する実験的研究 : 急性肺高血圧作成時に於ける右室内圧最大上昇速度(Rvmax dp/dt)の時相変動について
タイトルヨミウシツ シュウシュクジカン ニ カンスル ジッケンテキ ケンキュウ : キュウセイ ハイコウケツアツ サクセイジ ニ オケル ウシツナイアツ サイダイ ジョウショウソクド (rvmax dp/dt) ノ ジソウ ヘンドウ ニ ツイテ
タイトル別表記An Experimental Study on the Right Ventricular Systonic Time Interval : It's Time Relationship to Rvmax dp/dt in Experimentally Induced Pulmonary Hypertention
作成者池江, 喜信
作成者ヨミイケエ, ヨシノブ
作成者別表記Ikee, Yoshinobu
作成者所属山口大学医学部
内容記述(抄録等)This study was undertaken to investigate behaviors of right heart regarding ventricular systonic time interval (RVSTI) in acute pulmonary hypertension. Acute pulmonary hypertension was produced experimentally in 7 healthy mongrel dogs by injecting carbon grains suspemded in normal saline through a catheter placed in right ventricle. Increasing amounts of carbon grains were injected discontinuously montitoring pulmonary artery mean pressure (Pam). Intraventricular pressure curve, right ventricular maximum rate of pressure elevation (Rvmaxdp/dt) and ECG were recorded when Pam reached to arbitrarily selected 3 to 7 levels. RVSTI consisting of preejection period (PEP), ejection time (ET) and PEP/ET were measured. In addition, Rvmaxdp/dt, time interval berween Q wave on ECG to Rvmaxdp/dt (Q-Rvmaxdp/dt), and (Q-Rvmaxdp/dt) -RVPEP were also determined. The results were as followings ; 1. RVPEP increased correlatively with the elevation of pulmonary artery diastolic pressure (Pad). 2. Increase of contractile forces of right ventricle was associated with the elevation of Pad. 3. Q-Rvmaxdp/dt did not increase when Pad was elevated sufficiently enough to cause inerease of RVPEP. 4. (Q-Rvmaxdp/dt) - RVPEP shifted from positive scores to negative scores when Pad was elevated. As consequence, Rvmaxdp/dy seemed to occur prior to the end of RVPEP. Concluding remark ; The observed result in this study could be ascribed to neurohumoral reflex and/or homeometric autoregulation provoked by pulmonary embolism and resulting pulmonary hypertension, and, in part, to anatomical specificity of right ventricular wall.
本文言語jpn
主題医学
資料タイプtext
出版者山口大学医学会
出版者ヨミヤマグチ ダイガク イガッカイ
NII資料タイプ学術雑誌論文
査読の有無査読あり
ISSN0513-1731
NCIDAN00243156
学内刊行物(紀要等)山口医学
掲載誌名山口医学
26
1
開始ページ45
終了ページ58
発行日1977-06
著者版/出版社版その他
リポジトリIDB030026000106
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/B030026000106