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タイトル慢性心筋梗塞患者の左室弛緩特性 : 左室等容弛緩期における左室局所壁運動異常の左室弛緩特性に及ぼす影響
タイトルヨミマンセイ シンキン コウソク カンジャ ノ サシツ シカン トクセイ : サシツ トウヨウ シカンキ ニ オケル サシツ キョクショヘキ ウンドウ イジョウ ノ サシツ シカン トクセイ ニ オヨボス エイキョウ
タイトル別表記Left Ventricular Relaxation in Old Myocardial Infarction : Abnormal Regional Wall Motion during Isovolumic Relaxation and Its Effects on the Left Ventricular Relaxation
作成者矢田部, 左近
作成者ヨミヤタベ, サコン
作成者別表記Yatabe, Sakon
作成者所属山口大学医学部
内容記述(抄録等)The effects of the regionl left ventricular (LV) wall motion on the LV relaxation were studied in, 9 patients (pts) with old antero-septal myocardial infarction (OMI) who had an isolated disease of the left anterior descending coronary artery and in 8 normal subjects (NOR) who were diagnosed as atypical chest pain. LV silhoettes in the right anterior oblique view of the LV biplane cineangiogram (60 frame/sec) were outlined from the time of peak (-) dp/dt to the time of mitral valve opening. LV area was divided into 8 sectons by along (longitudinal) axis and by 3 short (transverse) axises which was perpendicular to the long axis and divided the long axis into the 4 equal distances. The areas of the 2 middle sections in the anterior (Aa) and the inferior (Ab) sides in these 8 sectons were measured, respectively. Basal and apical sections were excluded. During IRT in NOR group. Aa began to increase from 33.4 msec after peak (-) dp/dt, but Ab did not. In OMI group, on the other hand. Ab increased from 50 msec after peak (-) dp/dt, while Aa decreased, probably because of the passive shortening of the anterior segments by the expansion of the inferior segments. These wall motions during IRT suggest the shape change of LV. In OMI group, Ab/Aa began to decrease from 16.7 msec after peak (-) dp/dt, while in OMI group increased. The time course of the Ab/Aa could be reasonably fitted by a straight line (r≧0.9) in all cases. The slope of this line [28.2±16.0 (×10^<-3>) msec ; p<0.001]. In all of the OMI group, the upstroke pattern of negative dp/dt was convex-downward. In NOR group, however, the pattern was convex-upward. Time constant was significantly higher in OMI group (50.4±9.2 msec), compared to the NOR group (37.0±6.3 msec ; p<0.01). Thus, in OMI the lengthening of the LV wall occurs in the normally perfused region during IRT, which was accompanied with the passive shortening of the infarcted regions. This asynchronous wall motion in the OMI group was found to be reverse to that of the normal heart, and may cause impairment of the LV relaxation.
本文言語jpn
主題医学
資料タイプtext
出版者山口大学医学会
出版者ヨミヤマグチ ダイガク イガッカイ
NII資料タイプ学術雑誌論文
査読の有無査読あり
ISSN0513-1731
NCIDAN00243156
学内刊行物(紀要等)山口医学
掲載誌名山口医学
35
1
開始ページ23
終了ページ33
発行日1986-02
著者版/出版社版その他
リポジトリIDB030035000105
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/B030035000105