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タイトル高齢者における微量アミロイドの沈着とその意義
タイトルヨミコウレイシャ ニ オケル ビリョウ アミロイド ノ チンチャク ト ソノ イギ
タイトル別表記Microdeposits of Amyloid in the Aged and their Significance
作成者長沢, 孝明
作成者ヨミナガサワ, タカアキ
作成者別表記Nagasawa, Takaaki
作成者所属山口大学医学部
内容記述(抄録等)The incidence and the organ distribution of amyloid deposits in the aged human were studied. One hundred and ten autopsied cases over seventy years old without systemic amyloidosis were examined retrospectively by polarizing microscopy of Congo red stained sections. In eighty-one cases, amyloid deposits were found in at least one of the examined organs and the overall incidence was 73.6%. Although the incidence of amyloid deposits increased with age, e. g. 65. 3% in 70-74 years old, 77.1% in 75-79, 84.6% in over 80, this phenomenon was not statistically significant. The aorta showed higher incidence (56/110, 50.9%) than other organs, e. g. pancreas (41/110, 37.3%), brain (5/22, 22.7%), seminal vesicle (3/15, 20.0%), lung (5/106, 4.7%), adrenal gland (2/95, 2.1%), kidney (2/108, 1.9%) and the heart (1/106, 0.9%). These deposits were almost always minute except those of seminal vesicle. Different mechanisms of deposition and protein natures of these ”age-related” amyloid from one organ to another have been postulated. These microdeposits of amyloid are considered to be one of the morphological changes as a result of the aging process.
本文言語jpn
主題医学
資料タイプtext
出版者山口大学医学会
出版者ヨミヤマグチ ダイガク イガッカイ
NII資料タイプ学術雑誌論文
査読の有無査読あり
ISSN0513-1731
NCIDAN00243156
学内刊行物(紀要等)山口医学
掲載誌名山口医学
32
3
開始ページ235
終了ページ246
発行日1983-06
著者版/出版社版その他
リポジトリIDB030032000302
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/B030032000302