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タイトル感染マウス体内における回帰熱ボレリアの電子顕微鏡的観察
タイトルヨミカンセン マウス タイナイ ニ オケル カイキネツ ボレリア ノ デンシ ケンビキョウテキ カンサツ
タイトル別表記Electron microscopic studies on Borrelia duttonii in infected mice
作成者広瀬, 治子
作成者ヨミヒロセ, ハルコ
作成者別表記Hirose, Haruko
作成者所属山口大学医学部
内容記述(抄録等)To reveal the dynamic status of Borrelia duttonii in infected animals, kidney, liver, and spleen of mice were surveyed three days after inoculation of the organisms by a transmission electron microscope. Following observations were informative on the profiles of B. duttonii in the organs. (1) The borreliae were seen in all the organs observed, in kidney, liver, and spleen. (2) The borreliae were localized in various kinds of blood vessels including the sinusoidal or Disse's space. (3) A number of organisms attacked to the surface of the erythrocytes, but none were found in the cytoplasm of circulating erythrosytes. (4) The borreliae were found in phagocytic cells such ad neutrophils, macrophages and endothelial cells, but none was found in the sytoplasm of hepatocytes or epithelial cells of uriniferous tubules. (5) The organisms in macrophages were localized either in the phagosomes or in the phagocytized erythrocytes. (6) B. duttonii in the capillary lumen showed normal morphology, while those in phagocytes or in phagocytized erythrocytes showed a degenerated feature. The above findings suggested that injected B. duttonii proliferated in the capillary luman, and some od them were engulfed by ohagocytes by themselves or thgether with erythrocytes. It was also suggested that a few borreliae might be released from the phagocytes and proliferate again in the capillary luman.
本文言語jpn
主題医学
資料タイプtext
出版者山口大学医学会
出版者ヨミヤマグチ ダイガク イガッカイ
NII資料タイプ学術雑誌論文
査読の有無査読あり
ISSN0513-1731
NCIDAN00243156
学内刊行物(紀要等)山口医学
掲載誌名山口医学
38
5
開始ページ345
終了ページ364
発行日1989-10
著者版/出版社版その他
リポジトリIDB030038000502
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/B030038000502