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フルテキストURL2008010287.pdf ( 2.2MB ) 公開日 2010-04-16
タイトルReaginic and hemagglutinating antibody production in dogs infected with Dirofilaria immitis
作成者Hayasaki, Mineo
作成者ヨミハヤサキ, ミネオ
作成者別表記早崎, 峯夫
作成者所属山口大学農学部
内容記述(抄録等)The kinetics of reaginic and hemagglutinating antibody productions in dogs experimentally infected with Dirofilaria immitis was studied by passive cutaneous anaphylaxis reaction and indirect hemagglutination test. Reaginic antibody was first detected on the 65th day of infection, which coincided with the fourth molt of worm development. Although the antibody transiently disappeared on the 97th day, it reappeared, thereafter, and boosted when microfilaremia became evident. The reaginic activity of sera was completely deleted by heating at 56℃ for 60 min and by reduction and alkylation procedures. Sephadex G-200 gel filtration analysis indicates that reaginic activity was recovered in the ascending portion of the second (IgG) peak, suggesting molecular weight slightly greater than that of IgG. Hemagglutinating antibody was first observed on the l9th day of infection and then, steadily increased until the end of the study. Hemagglutinating antibody responses showed the pattern of two distinct peaks which coincided both with the fourth larval molt and the occurrence of microfilaremia.
本文言語eng
資料タイプtext
ファイル形式application/pdf
出版者日本獣医学会
出版者ヨミニホン ジュウイ ガッカイ
NII資料タイプ学術雑誌論文
査読の有無査読あり
ISSN0021-5295
NCIDAN00191788
掲載誌名日本獸醫學雜誌
掲載誌名別表記The Japanese journal of veterinary science
44
1
開始ページ63
終了ページ70
発行日1982
関連情報URL(IsPartOf)http://www.jstage.jst.go.jp/browse/jvms/-char/ja
Dirofilaria immitis infection and dirofilariosis : an animal model of human filariosis
著者版/出版社版出版社版
リポジトリID2008010287
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/2008010287