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タイトル腸管内胆汁酸分析による胆道再建術式の検討
タイトルヨミチョウカンナイ ンタンジュウサン ブンセキ ニ ヨル タンドウ サイケン ジュツシキ ノ ケントウ
タイトル別表記Evaluation of biliary tract reconstruction procedures by analysis of bile acids in the jejunal lumen
作成者山本, 達人
作成者ヨミヤマモト, タツヒト
作成者別表記Yamamoto, Tatsuhito
作成者所属山口大学医学部
内容記述(抄録等)The purpose of this study was to evaluate the composition of various bile acids and the presence of anaerobes in jejunal fluid following B-I and B-II biliary reconstruction in dogs. B-I reconstruction, in which bile mixes with ciba, was performed in 16 dogs, including 8 with cholecystoduodenostomy (C-D) and 8 with cholecystojejunostomy (C-J), and B-II reconstruction with Roux-Y cholecystojejunostomy, in which bile flows into the jejunal limb, was performed in 8 dogs (R-Y). In six R-Y, unconjugated bile acids or secondary bile acids in jejunal fluid increased, while these findings were observed in only two C-J and in none of C-D. Unconjugated bile acids and secondary bile acids showed a tendency to increase in B-II, in contrast with B-I. Anaerobes were detected in about 67% of B-II jejunal fluid samples, higher than in B-I jejunal fluic samples. The above-mentioned increase in unconjegated bile acids and secondary bile acids in B-II was thought to be associated with bacterial overgrowth in the jejunal loop. These results suggest that conjegated bile acids, which are essential for fat digestion and absorption, decrease more markedly following B-II recinstruction than following B-I reconstruction, and that B-I reconstruction is superior in preserving the capacity for digestion and absorpation.
本文言語jpn
主題医学
資料タイプtext
出版者山口大学医学会
出版者ヨミヤマグチ ダイガク イガッカイ
NII資料タイプ学術雑誌論文
査読の有無査読あり
ISSN0513-1731
NCIDAN00243156
学内刊行物(紀要等)山口医学
掲載誌名山口医学
40
1
開始ページ85
終了ページ92
発行日1991-02
著者版/出版社版その他
リポジトリIDB030040000110
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/B030040000110