| フルテキストURL | A050056000103.pdf ( 921.5KB ) 公開日 2010-04-19
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| タイトル | A case of Castleman's disease of hyaline-vascular type associated with pure red cell aplasia which was successfully treated with cyclosporine |
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| 作成者 | Suzukawa, Munehiro
Kondo, Manabu
Sugiyama, Akiko
Tominaga, Takayuki
Shinohara, Kenji
Kamei, Toshiaki
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| 作成者ヨミ | スズカワ, ムネヒロ
コンドウ, マナブ
スギヤマ, アキコ
トミナガ, タカユキ
シノハラ, ケンジ
カメイ, トシアキ
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| 内容記述（抄録等） | A 70-year-old female complained of palpitation. CBC demonstated anemia and bone marrow aspiration smear demonstrated absence of erythroid hematopoietic cells, and pure red cell aplasia (PRCA) was diagnosed. Computed tomography (CT) demonstrated abdominal tumor. Biopsy of the abdominal tumor showed proliferation of lymph follicles with small and medium-sized lymphocytes, angiofollicular pattern in their center, and hyalinization around the surrounding tissue. Based on these findings, Castleman's disease (CD) of hyaline-vascular (HV) type was diagnosed. Since anemia progressed, a possible relation between the pathogenesis of PRCA and CD was considered. Therefore, prednisolone (PSL) was dministered for two months as well as two courses of COP (cyclophosphamide, oncovin and prednisolone) chemotherapy and 40Gy radiation to the abdominal tumor. After these treatments, the size of abdominal tumor decreased, but PRCA did not improve. Subsequently cyclosporine was administered for five months, and was effective for the improvement of anemia. These results indicated the immunological pathogenesis of PRCA even in Castleman's disease of hyaline-vascular type.
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| 本文言語 | eng
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| 著者キーワード | Castleman's disease
hyaline-vascular type
pure red cell aplasia
cyclosporine
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| 資料タイプ | text |
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| ファイル形式 | application/pdf |
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| 出版者 | Yamaguchi University School of Medicine
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| NII資料タイプ | 紀要論文 |
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| 学内刊行物(紀要等) | The bulletin of the Yamaguchi Medical School |
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| 掲載誌名 | The bulletin of the Yamaguchi Medical School |
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| 巻 | 56 |
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| 号 | 1-2 |
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| 開始ページ | 15 |
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| 終了ページ | 19 |
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| 発行日 | 2009 |
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| 関連情報URL(IsPartOf) | http://ds.cc.yamaguchi-u.ac.jp/~bulletin/index.html
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| 著者版/出版社版 | 出版社版 |
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| リポジトリID | A050056000103 |
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| 地域区分 | 山口大学
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| URI | http://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A050056000103 |
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