| フルテキストURL | A050062000306.pdf ( 993.2KB ) 公開日 2016-05-20
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| タイトル | Duration of prophylaxis against venous thromboembolism with low molecular weight heparin (enoxaparin) after surgery for abdominal and esophageal cancer : a single institution, prospective, randomized trial in japan |
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| 作成者 | Katsura, Shunsaku
Enoki, Tadahiko
Kugimiya, Naruji
Takemoto, Yoshihiro
Oka, Kazuhito
Harada, Eijiro
Hamano, Kimikazu
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| 作成者ヨミ | カツラ, シュンサク
エノキ, タダヒコ
クギミヤ, ナルジ
タケモト, ヨシヒロ
オカ, カズヒト
ハラダ, エイジロウ
ハマノ, キミカズ
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| 作成者別表記 | 桂, 春作
榎, 忠彦
釘宮, 成二
竹本, 圭宏
岡, 一斉
原田, 栄二郎
濱野, 公一
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| 作成者所属 | 山口大学大学院医学系研究科（医学）
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| 内容記述（抄録等） | Background: The optimal duration of thromboprophylaxis after surgery for cancer has not been clearly defined in Japan. The aim of this prospective study was to evaluate the efficacy and safety of 3 days of thromboprophylaxis in comparison to 10 days of thromboprophylaxis with low molecular weight heparin (enoxaparin) in patients undergoing elective surgery for abdominal and esophageal cancer.Methods: The study population included patients who were over 40 years of age and who were planning to undergo elective surgery for abdominal and esophageal cancer. 101 patients were randomly assigned to the short thromboprophylaxis (3 days) and long thromboprophylaxis (10 days) groups. Finally, after applying the exclusion criteria, we evaluated 45 patients in each group. The primary efficiency endpoint was the incidence of venous thromboembolism between day 11 and the day of discharge.Results: The incidence rates of distal deep vein thrombosis (DVT) after surgery were 6.7% and 8.9% in the short and long thromboprophylaxis groups, respectively. (p = 0.50). There was no significant difference. Conclusions: We concluded that if pharmacological thromboprophylaxis with enoxaparin was combined with mechanical methods in patients undergoing elective surgery for cancer, then the adequate duration of routine thromboprophylaxis with enoxaparin was only 3 days.
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| 本文言語 | eng
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| 著者キーワード | low molecular weight heparin
enoxaparin
venous thromboembolism
surgery
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| 資料タイプ | text |
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| ファイル形式 | application/pdf |
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| 出版者 | Yamaguchi University School of Medicine
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| NII資料タイプ | 紀要論文 |
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| ISSN | 0513-1812
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| NCID | AA00594272
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| 学内刊行物(紀要等) | The bulletin of the Yamaguchi Medical School |
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| 掲載誌名 | The bulletin of the Yamaguchi Medical School |
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| 巻 | 62 |
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| 号 | 3-4 |
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| 開始ページ | 59 |
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| 終了ページ | 65 |
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| 発行日 | 2015 |
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| 著者版/出版社版 | 出版社版 |
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| リポジトリID | A050062000306 |
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| 地域区分 | 山口大学
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| URI | http://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A050062000306 |
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