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フルテキストURLA020041000309.pdf ( 21.1MB ) 公開日 2010-04-19
タイトルCharacteristic Ultrastructural Findings in Metablic and Storage Diseases
作成者Ishihara, Tokuhiro
Takahashi, Mutsuo
Gondo, Toshikazu
Kawano, Hiroo
Hoshii, Yoshinobu
Tamura, Suguru
Yamashita, Yoshimi
Yokota, Tadaaki
Kamei, Toshiaki
Koga, Mayumi
Uchino, Fumiya
作成者ヨミイシハラ, トクヒロ
タカハシ, ムツオ
ゴンドウ, トシカズ
カワノ, ヒロオ
ホシイ, ヨシノブ
タムラ, スグル
ヤマシタ, ヨシミ
ヨコタ, タダアキ
カメイ, トシアキ
コガ, マユミ
ウチノ, フミヤ
作成者所属山口大学医学部
内容記述(抄録等)Electron microscopic observations performed with immunoelectron microscopy and specific cytochemical stainings play an important role in the diagnosis of diseases affectingcarbohydrate, lipid, protein, and mineral metabolism. The characteristic ultrastructural changes in affected cels of metabolic diseases are summarized as follows: (1) many glycogen granules in glycogenosis type Ⅰ; (2) many glycogen granules in glycogenosis type Ⅲ; (3) glycogenosomes in glycogenosis type Ⅱ; (4) curvilinear tubular structures in Farber's disease; (5) mylin-like figures in Niemann-Pick's disease, and in splenic macrophages with idiopathic thrombocytopenic purpura; (6) tubular structures in hemolytic anemia resulting from overproduction of adenosine deaminase; (7) zebra bodies or membranous cytoplasmic bodies in Fabry's disease; (8) vacuoles containing ggranular and flocculent materials in Hurler's syndrome; (9) vacuoles in sialidosis; (10) vacuoles containing granular, flocculent and myelin-like figures in I-cell disease; (11) membrane-like structures in glycogenosis type Ⅳ; (12) membrabe-like structures showing a positive reaction with Thiery stains for demonstrating carbohydrate materials in Lafora's disease; (13) nonbranching fibrils, measuring 7-15 nm in width, in the extracellular space and rarely in a few cells from systemic amyloidosis and localized amyloidosis (using immunoelectron microscopy with antibodies and localized amyloidosis (using immunoelectron microscopy with antibodies to AA, Aλ, Aκ, β2-microglobulin, and β/A4, we have been able to identify amyloid fibrils in various kinds of amyloidosis); (14) vacuolar inclusions with limiting membrane varying in diameter from 200-300 μm to several μm in polyvinyl pyrrolidone thesaurosis; and (15) aurosomes in patients with Felty's syndrome who have received gold sodium thiomalate.
本文言語eng
著者キーワードLeishmania
Major surface glycoprotein
Amastigone and promastigone expression
Immunofluorescence method
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
41
3-4
開始ページ113
終了ページ142
発行日1994-12
著者版/出版社版出版社版
リポジトリIDA020041000309
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020041000309