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フルテキストURLA050060000302.pdf ( 1.5MB ) 公開日 2014-06-19
タイトルPneumonia after esophageal surgery for squamous cell carcinoma : impact of HLA-DR antigen expression on monocytes
作成者Takemoto, Yoshihiro
Enoki, Tadahiko
Tanaka, Yuuya
Harada, Eijirou
Hamano, Kimikazu
作成者ヨミタケモト, ヨシヒロ
エノキ, タダヒコ
タナカ, ユウヤ
ハラダ, エイジロウ
ハマノ, キミカズ
作成者別表記竹本, 圭宏
榎, 忠彦
田中, 裕也
原田, 栄二郎
濱野, 公一
作成者所属山口大学医学部附属病院
山口大学大学院医学系研究科(医学)
内容記述(抄録等)Although surgical techniques and perioperative management of esophageal surgery have improved remarkably, morbidity and mortality remain high in comparison with those associated with other procedures. Mortality after esophageal surgery is primarily determined by the development of pulmonary complications. This study included 41 patients who underwent esophageal resection and reconstruction for thoracic esophageal cancer. We evaluated changes in the levels of interleukin (IL)-6 and IL-10, the type 1/type 2 T-helper (Th1/Th2) cell balance, and the expression of HLA-DR antigen on the surface of monocytes after surgery.The pneumonia group tended to have undergone surgeries of a longer duration and had higher serum IL-6 levels on postoperative day 1 than the no pneumonia group. However, serum IL-10 levels or the Th1/Th2 cell balance did not differ significantly between the 2 groups. HLA-DR antigen expression on monocytes was significantly lower in the pneumonia group than in the no pneumonia group on postoperative day 3. In conclusion, estimation of operative time, serum IL-6 levels, and HLA-DR expression on monocytes may provide a method for predicting postoperative pneumonia.
本文言語eng
著者キーワードPneumonia
esophageal cancer
surgery
HLA-DR antigen expression on monocytes
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
60
3-4
開始ページ57
終了ページ63
発行日2013
著者版/出版社版出版社版
リポジトリIDA050060000302
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A050060000302