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フルテキストURLA020032000102.pdf ( 3.2MB ) 公開日 2010-04-19
タイトルPrimary gastric choriocarcinoma associated with adenocarcinoma-A Case Report with Immunohistochemical Study-
作成者Kamei, Toshiaki
Maeda, Junpei
Kondo, Naotsugu
Hongo, Hiroshi
Yanagihara, Teruo
Nakamura, Isao
Ishihara, Tokuhiro
Okuzono, Yoshiko
Gondo, Toshikazu
Fujihara, Shigeyoshi
作成者ヨミカメイ, トシアキ
マエダ, ジュンペイ
コンドウ, ナオツグ
ホンゴウ, ヒロシ
ヤナギハラ, テルオ
ナカムラ, イサオ
イシハラ, トクヒロ
オクゾノ, ヨシコ
ゴンドウ, トシカズ
フジハラ, シゲヨシ
作成者所属山口大学医学部
内容記述(抄録等)A case of a 69 year old female with primary gastric choriocarcinoma was presented with spesial reference to histogenesis by using the immunohistochemical tequnique (PAP method). The gastric tumor in this case was histologically diagnosed as choriocarcinoma coexistent with adenocarcinoma. From hormonal standpoint, the diagnosis was confirmed by recognition of high HCG titers in both the serum and tumor. The primary focus of the choriocarcinoma was detected neither in the genitourinary tract nor in the mediastinum in spite of a thorough autopsy. By PAP method tumor cells of choriocarcinoma showed high positive reaction only to anti-HCG antiserum and less positive to anti-HPL and SP1 antisera in contrast to those of uterine choriocarcinoma with high positive reaction to anti-HCG, HPL and SP1 antisera. Tumor cells of adenocarcinoma showed positivity to anti-CEA and anti-AFP antisera by the same method. These results indicate that gastric choriocarcinoma might be functionally defferent from gestational choriocarcinoma. Moreover, tumor cells of adenocarcinomatous lesion have some resemblance to embrynal carcinoma morphologically and immunohistochemically. Therefore, the origin of gastric choriocarcinoma seemed to be morphological retrodifferentiation of tumor cells to embryonal ectoderm such as trophoblastic cells.
本文言語eng
著者キーワードchoriocarcinoma
adenocarcinoma
stomach
immuoohistochemistry
histogenesis
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
32
1
開始ページ11
終了ページ19
発行日1985-12
著者版/出版社版出版社版
リポジトリIDA020032000102
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020032000102