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フルテキストURLA020032000101.pdf ( 3.9MB ) 公開日 2010-04-19
タイトルUltrastructural Study on the Spleens of 28 Patients with ITP:Platelet Phagocytosis of Cordal Macrophages
作成者Ishihara, Tokuhiro
Yamashita, Yoshimi
Gondo, Toshikazu
Yokota, Tadaaki
Kamei, Toshiaki
Takahashi, Mutsuo
Uchino, Fumiya
Matsumoto, Noboru
作成者ヨミイシハラ, トクヒロ
ヤマシタ, ヨシミ
ゴンドウ, トシカズ
ヨコタ, タダアキ
カメイ, トシアキ
タカハシ, ムツオ
ウチノ, フミヤ
マツモト, ノボル
作成者所属山口大学医学部
内容記述(抄録等)Spleens of 28 patients with idiopatic thrombocytopenic purpura have been observed histologically, immunohistologically and electron microscopically. Spleens of fifteen patients had the foamy cells in the red pulp. Some foamy cells had positive materials for anti-human platelet antibody, using the unlabelled immunoperoxidase method. Electorn microscopically, many platelets in varying stages of intracellular digestion from intact-appearing platelets to myelinlike materials were disclosed in the foamy cells. We suggest that there are two types of the macrophage in the spleen from patients with ITP. One does not reveal foamy cytoplasm, because phagocytized are immediately digested by the lysosomal enzyme within cytoplasm of macrophages. The other has foamy cytoplasm, because phagocytized platelets are incompletely digested and remain as myelinlike materials within cytoplasm of macrophages.
本文言語eng
著者キーワードITP
Ultrastructure
Spleen
Platelet
Cordal macrophage
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
32
1
開始ページ1
終了ページ9
発行日1985-12
著者版/出版社版出版社版
リポジトリIDA020032000101
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020032000101