| フルテキストURL | A020032000101.pdf ( 3.9MB ) 公開日 2010-04-19
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| タイトル | Ultrastructural Study on the Spleens of 28 Patients with ITP：Platelet Phagocytosis of Cordal Macrophages |
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| 作成者 | Ishihara, Tokuhiro
Yamashita, Yoshimi
Gondo, Toshikazu
Yokota, Tadaaki
Kamei, Toshiaki
Takahashi, Mutsuo
Uchino, Fumiya
Matsumoto, Noboru
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| 作成者ヨミ | イシハラ, トクヒロ
ヤマシタ, ヨシミ
ゴンドウ, トシカズ
ヨコタ, タダアキ
カメイ, トシアキ
タカハシ, ムツオ
ウチノ, フミヤ
マツモト, ノボル
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| 作成者所属 | 山口大学医学部
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| 内容記述（抄録等） | Spleens of 28 patients with idiopatic thrombocytopenic purpura have been observed histologically, immunohistologically and electron microscopically. Spleens of fifteen patients had the foamy cells in the red pulp. Some foamy cells had positive materials for anti-human platelet antibody, using the unlabelled immunoperoxidase method. Electorn microscopically, many platelets in varying stages of intracellular digestion from intact-appearing platelets to myelinlike materials were disclosed in the foamy cells. We suggest that there are two types of the macrophage in the spleen from patients with ITP. One does not reveal foamy cytoplasm, because phagocytized are immediately digested by the lysosomal enzyme within cytoplasm of macrophages. The other has foamy cytoplasm, because phagocytized platelets are incompletely digested and remain as myelinlike materials within cytoplasm of macrophages.
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| 本文言語 | eng
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| 著者キーワード | ITP
Ultrastructure
Spleen
Platelet
Cordal macrophage
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| 主題 | 医学
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| 資料タイプ | text |
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| ファイル形式 | application/pdf |
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| 出版者 | Yamaguchi University Graduate School of Medicine
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| NII資料タイプ | 紀要論文 |
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| ISSN | 0513-1812
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| NCID | AA00594272
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| 学内刊行物(紀要等) | The bulletin of the Yamaguchi Medical School |
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| 掲載誌名 | The bulletin of the Yamaguchi Medical School |
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| 掲載誌名別表記 | 山口医科大学紀要 |
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| 巻 | 32 |
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| 号 | 1 |
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| 開始ページ | 1 |
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| 終了ページ | 9 |
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| 発行日 | 1985-12 |
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| 著者版/出版社版 | 出版社版 |
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| リポジトリID | A020032000101 |
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| 地域区分 | 山口大学
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| URI | http://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020032000101 |
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