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フルテキストURLA020041000104.pdf ( 2.8MB ) 公開日 2010-04-19
タイトルPermeability of Horseradish Peroxidase in the Area of Cold Injury-induced Brain Edema -Time-sequence observation of cerebral micro-blood vessels-
作成者Akimura, Tatuo
Orita, Tetsuji
Ito, Haruhide
作成者ヨミアキムラ, タツオ
オリタ, テツジ
イトウ, ハルヒデ
作成者所属山口大学医学部
内容記述(抄録等)A cold-lesion injury of mild degree was induced in the parietal cortex of adult rats by application of a cooled metal plate. Twenty four hours after injury, the ultrastructure of the micro-blood vessels in the edema area was observed, following intravenous administration of horseradish peroxidase (HRP). The circulation time of HRP was restricted to a maximum of 40 min and the transit time of HRP across the cerebral endothelium of the edema area was investigated morphologically. At least 5 min was required for intravenously injected HRP to cross the endothelium in the area of vasogenic brain edema following cold-lesion injury. In addition to the capillaries, the arterioles appeared to play an important role in the increased permeability of cerebral blood vessels after cold-lesion injury. The increased permeability was thought to be due to increased vesicular transport and damage to endothelial plasma membranes, but the priority of these factors could not be determined using this method.
本文言語eng
著者キーワードHepatocelluar carcinoma
Hemobilia
Obstructive jaundice
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
41
1-2
開始ページ19
終了ページ24
発行日1994-06
著者版/出版社版出版社版
リポジトリIDA020041000104
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020041000104