| フルテキストURL | A020041000104.pdf ( 2.8MB ) 公開日 2010-04-19
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| タイトル | Permeability of Horseradish Peroxidase in the Area of Cold Injury-induced Brain Edema -Time-sequence observation of cerebral micro-blood vessels- |
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| 作成者 | Akimura, Tatuo
Orita, Tetsuji
Ito, Haruhide
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| 作成者ヨミ | アキムラ, タツオ
オリタ, テツジ
イトウ, ハルヒデ
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| 作成者所属 | 山口大学医学部
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| 内容記述（抄録等） | A cold-lesion injury of mild degree was induced in the parietal cortex of adult rats by application of a cooled metal plate. Twenty four hours after injury, the ultrastructure of the micro-blood vessels in the edema area was observed, following intravenous administration of horseradish peroxidase (HRP). The circulation time of HRP was restricted to a maximum of 40 min and the transit time of HRP across the cerebral endothelium of the edema area was investigated morphologically. At least 5 min was required for intravenously injected HRP to cross the endothelium in the area of vasogenic brain edema following cold-lesion injury. In addition to the capillaries, the arterioles appeared to play an important role in the increased permeability of cerebral blood vessels after cold-lesion injury. The increased permeability was thought to be due to increased vesicular transport and damage to endothelial plasma membranes, but the priority of these factors could not be determined using this method.
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| 本文言語 | eng
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| 著者キーワード | Hepatocelluar carcinoma
Hemobilia
Obstructive jaundice
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| 主題 | 医学
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| 資料タイプ | text |
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| ファイル形式 | application/pdf |
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| 出版者 | Yamaguchi University Graduate School of Medicine
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| NII資料タイプ | 紀要論文 |
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| ISSN | 0513-1812
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| NCID | AA00594272
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| 学内刊行物(紀要等) | The bulletin of the Yamaguchi Medical School |
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| 掲載誌名 | The bulletin of the Yamaguchi Medical School |
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| 掲載誌名別表記 | 山口医科大学紀要 |
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| 巻 | 41 |
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| 号 | 1-2 |
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| 開始ページ | 19 |
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| 終了ページ | 24 |
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| 発行日 | 1994-06 |
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| 著者版/出版社版 | 出版社版 |
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| リポジトリID | A020041000104 |
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| 地域区分 | 山口大学
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| URI | http://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020041000104 |
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