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フルテキストURLA020049000309.pdf ( 263.7KB ) 公開日 2010-04-19
タイトルA case of Maxillary Sinus Plasmacytoma and Analysis of Cellular Biological Features
作成者Ita, Masamichi
Okafuji, Masaki
Noutomi, Yasuyuki
Saito, Yukoh
Sasaki, Kohsuke
作成者ヨミイタ, マサミチ
オカフジ, マサキ
ノウトミ, ヤスユキ
ササキ, コウスケ
作成者所属山口大学医学部
内容記述(抄録等)Extramedullary plasmacytoma is a rare malignant tumor that generally arises in the head and neck region. We encountered a plasmacytoma located in the maxilla, maxilllary sinus, and ethmoidal sinuses. The tumor was composed of premature cells showing positive staining for λlight chain immunoglobulin. Several types of examination, including M protein analysis, reled out multiple myeloma. After a debulking operation, a total of 50 Gy of radiation failed to shrink the tumor. To prevent the tumor from progressing to multiple myeloma, the patient underwent chemotherapy. After this treatment, the tumor showed no growth. Flow cytometry and comparative genomic hybridization studies showed the tumor DNA to be diploid, containing few chromosomal aberrations. On the basis of these findings, it was thought that the tumor malignancy of plasmacytoma might be relevant to DNA ploidy pattern and chromosomal aberration.
本文言語eng
著者キーワードPlasmacytoma
Maxillary sinus
DNA cotent
comparative genomic hybridization
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
49
3-4
開始ページ107
終了ページ113
発行日2002-12
著者版/出版社版出版社版
リポジトリIDA020049000309
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020049000309