Japanese | English

トップページへ戻る

詳細

   
フルテキストURLA020039000304.pdf ( 1.8MB ) 公開日 2010-04-19
タイトルThe Affects of Long-term Oral Vitamin D Treatment on Abdominal Aortic Calcification and Vertebral Bone Mineral Content in the Elderly Patients with Osteoporosis
作成者Sugihara, Nobuyuki
Matsuzaki, Masunori
Furutani, Kaneto
Kato, Yukio
Miyawaki, Muneo
作成者ヨミスギハラ, ノブユキ
マツザキ, マスノリ
フルタニ, カネト
カトウ, ユキオ
ミヤワキ, ムネオ
作成者所属山口大学医学部
内容記述(抄録等)We investigated the affects of long-term oral vitamin D treatment on aortic wall and vetebral bone in the elderly patients with osteoporosis by computed tomography. We calculated the aortic calcification index (ACI) of calcification volume to aortic volume wuthin 10 slices in the lower abdominal aorta, and measured the bone mineral content (BMC) of three lumbar vertebral bodies (the 2nd, 3rd, 4th) using a calibration phantom. We compared the ACIs and BMCs between 15 patients under no vitamin D therapy (10 men, 5 women, 79±7 yrs)(Group-Ⅰ) and 17 patients with osteoporosis under vitamin D therapy (4 men, 13 women, 75±6 yrs)(Group-Ⅱ). The patients in Group-Ⅱ received vitamin D everyday to sum up the duration into 849±333 days and the dosage into 604±323μg. ACI slightly increased from 9.2±7.2 to 11.0±8.5% in Group-Ⅰ(NS), and similarly increased from 9.3±10.6 to 12.2±12.9% in Group-Ⅱ(NS). Percent change of ACI was higher in Group-Ⅱ(58±73%) than in Group-Ⅰ(32±52%)(NS). BMC slightly decreased from 63.2±40.6 to 62.4±45.4mg/c? in Group-Ⅰ(NS), but increased a little from 57.8±51.4 to 63.3±44.6mg/c? in Group-Ⅱ(NS). These results suggest that there is a tendency to increase in both aortic calcification and bone mineral content under an event small dosage but long-term treatment of oral vitamin D.
本文言語eng
著者キーワードAbdominal aortic calcification
Vitamin D
Atherosclerosis
Osteoporosis
Bone mineral content
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
39
3-4
開始ページ55
終了ページ63
発行日1992-12
著者版/出版社版出版社版
リポジトリIDA020039000304
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020039000304