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フルテキストURLA020046000106.pdf ( 1.7MB ) 公開日 2010-04-19
タイトルTroglitazone-Induced Liver Injury Diagnosed by a Laparoscopic Examination in Its Asymptomatic Stage
作成者Inoue, Yasushi
Yamada, Tetsuya
Katsuki, Kensaku
Kato, Akira
Kodama, Takahiro
Kamei, Toshiaki
作成者ヨミイノウエ, ヤスシ
ヤマダ, テツヤ
カツキ, ケンサク
カトウ, アキラ
コダマ, タカヒロ
カメイ, トシアキ
作成者所属山口大学医学部
内容記述(抄録等)A 56-year-old diabetic woman had been taking glibenclamide (10 mg daily) plus voglibose (0.6 mg daily) for recent 4 years without a successful response. Three months after troglitazone (400 mg daily) was started in addition to glibenclamide, liver dysfunction was found by chance. She demonstrated no symptoms, histological examination, however, revealed a substantial hepatocelluar necrosis mainly in the peri-central vein areas, which was consistent with an idiosyncratic drug reaction. Since troglitazoneinduced liver dtsfunction was strongly suggested, administaration of troglitazone was terminated and abnormal values of liver-chemistry returned to normal in two months.
本文言語eng
著者キーワードtroglitazone
diabetes mellitus
liver injury
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
46
1-2
開始ページ41
終了ページ44
発行日1999-06
著者版/出版社版出版社版
リポジトリIDA020046000106
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020046000106