| フルテキストURL | A050058000301.pdf ( 1.9MB ) 公開日 2012-03-16
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| タイトル | The effects of three types of stress on fos expression in the hypothalamic paraventricular nucleus, hippocampus and amygdala in female rats at different stages of pregnancy |
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| 作成者 | Tanaka, Masuo
Hayashi, Shunsuke
Fujioka, Takashi
Tobe, Ikuyo
Nakamura, Shoji
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| 作成者ヨミ | タナカ, マスオ
ハヤシ, シュンスケ
フジオカ, タカシ
トベ, イクヨ
ナカムラ, ショウジ
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| 作成者別表記 | 田中, 増郎
林, 俊輔
富士岡, 隆
戸部, 郁代
中村, 彰治
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| 作成者所属 | 山口大学大学院医学系研究科（医学）
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| 内容記述（抄録等） | Using immunohistochemistry to reveal the Fos protein (a marker of neuronal activation), the present experiments examined whether there were differences in the responses of the paraventricular nucleus (PVN), hippocampus, and amygdala of pregnant rats exposed to three types of stressors (restraint, immobilization, and communication-box stress), all having inherently different severities, at three pregnancy stages (6 days into pregnancy, or P6, early-pregnancy), P12 (mid-pregnancy) and P18 (late-pregnancy). The parvocellular PVN was activated by all three stressors almost equally at all pregnancy stages. The magnocellular PVN appeared to become more active without stressors in mid-pregnancy than in early-pregnancy. The stress responses of the hippocampal dentate gyrus to immobilization and communication-box stress, and that of the basolateral amygdala to immobilization stress in pregnant females, were greater in mid-pregnancy than at the other pregnancy stages. The magnocellular PVN was more sensitive to communication-box stress in late-pregnancy than at the other pregnancy stages, while the hippocampal CA3 and medial amygdala were less sensitive to communication-box stress and to restraint stress in late-pregnancy than at the other pregnancy stages, respectively.These results suggest that the responses of the PVN, hippocampus, and amygdala in pregnant female rats to different stressors were variable at different pregnancy stages.
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| 本文言語 | eng
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| 著者キーワード | maternal stress
psychological stress
physical stress
mid-pregnancy
pregnancy stage
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| 資料タイプ | text |
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| ファイル形式 | application/pdf |
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| 出版者 | Yamaguchi University School of Medicine
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| NII資料タイプ | 紀要論文 |
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| ISSN | 0513-1812
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| NCID | AA00594272
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| 学内刊行物(紀要等) | The bulletin of the Yamaguchi Medical School |
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| 掲載誌名 | The bulletin of the Yamaguchi Medical School |
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| 巻 | 58 |
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| 号 | 3-4 |
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| 開始ページ | 19 |
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| 終了ページ | 30 |
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| 発行日 | 2011 |
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| 著者版/出版社版 | 出版社版 |
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| リポジトリID | A050058000301 |
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| 地域区分 | 山口大学
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| URI | http://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A050058000301 |
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