Japanese | English

トップページへ戻る

詳細

   
フルテキストURLA050058000301.pdf ( 1.9MB ) 公開日 2012-03-16
タイトルThe effects of three types of stress on fos expression in the hypothalamic paraventricular nucleus, hippocampus and amygdala in female rats at different stages of pregnancy
作成者Tanaka, Masuo
Hayashi, Shunsuke
Fujioka, Takashi
Tobe, Ikuyo
Nakamura, Shoji
作成者ヨミタナカ, マスオ
ハヤシ, シュンスケ
フジオカ, タカシ
トベ, イクヨ
ナカムラ, ショウジ
作成者別表記田中, 増郎
林, 俊輔
富士岡, 隆
戸部, 郁代
中村, 彰治
作成者所属山口大学大学院医学系研究科(医学)
内容記述(抄録等)Using immunohistochemistry to reveal the Fos protein (a marker of neuronal activation), the present experiments examined whether there were differences in the responses of the paraventricular nucleus (PVN), hippocampus, and amygdala of pregnant rats exposed to three types of stressors (restraint, immobilization, and communication-box stress), all having inherently different severities, at three pregnancy stages (6 days into pregnancy, or P6, early-pregnancy), P12 (mid-pregnancy) and P18 (late-pregnancy). The parvocellular PVN was activated by all three stressors almost equally at all pregnancy stages. The magnocellular PVN appeared to become more active without stressors in mid-pregnancy than in early-pregnancy. The stress responses of the hippocampal dentate gyrus to immobilization and communication-box stress, and that of the basolateral amygdala to immobilization stress in pregnant females, were greater in mid-pregnancy than at the other pregnancy stages. The magnocellular PVN was more sensitive to communication-box stress in late-pregnancy than at the other pregnancy stages, while the hippocampal CA3 and medial amygdala were less sensitive to communication-box stress and to restraint stress in late-pregnancy than at the other pregnancy stages, respectively.These results suggest that the responses of the PVN, hippocampus, and amygdala in pregnant female rats to different stressors were variable at different pregnancy stages.
本文言語eng
著者キーワードmaternal stress
psychological stress
physical stress
mid-pregnancy
pregnancy stage
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
58
3-4
開始ページ19
終了ページ30
発行日2011
著者版/出版社版出版社版
リポジトリIDA050058000301
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A050058000301