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フルテキストURLA020020000105.pdf ( 371.5KB ) 公開日 2010-04-16
タイトルRadioprotective Action of SH Compounds Ⅲ. Effects of Aminoethyliosothjuronium Br. HBr, Cysteamine and 2-Mercaptopropionylglycine Against Mitotic Delay Induced By X-Rays.
作成者Kawasaki, Shoji
作成者ヨミカワサキ, ショウジ
作成者所属山口大学医学部
内容記述(抄録等)Protection by SH compounds (MPG, cysteamine and AET) against the mitotic delay induced by X-irradiation in Ehrlich ascites tumor cells was studied. With exposure to 200 rads, the mitotic delay time and its recovery of the group treated with SH compounds (0.5 mg MPG, 2 mg cysteamine and 3 mg AET) were similar to those of non-treated group up to 12 hours after irradiation, but at 12 hours and rater the mitotic index of the groups treated with SH compounds was at a much higher level. The recovery rate from the mitotic inhibition became faster by increasing the concentration of the SH compounds (4 mg cysteamine or 6 mg AET) injected. Similar effects of SH compound were observable in the case of 400-rad irradiation. Increasing the concentration of the SH compound (4 mg cysteamine or 6 mg AET) treated, the recovery of mitosis was accelerated remarkably. From these data, it is suggested that the SH compound has a differential protective effect on mitotic delay the cell cycle.
本文言語eng
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
20
1-2
開始ページ45
終了ページ51
発行日1973-06
著者版/出版社版出版社版
リポジトリIDA020020000105
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020020000105