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フルテキストURLA020041000311.pdf ( 1.6MB ) 公開日 2010-04-19
タイトルEstablishment and Characterization of a New Human Esophageal Cancer Cell Line (YES-2)
作成者Nakamura, Masayuki
Murakami, Takuo
Sakata, Koichiro
Kusanagi, Hiroshi
Saeki, Toshihiro
Uchisako, Hiroyuki
Hayashi, Hiroto
Tangoku, Akira
Suzuki, Takashi
作成者ヨミナカムラ, マサユキ
ムラカミ, タクオ
サカタ, コウイチロウ
クサナギ, ヒロシ
サエキ, トシヒロ
ウチサコ, ヒロユキ
ハヤシ, ヒロト
タンゴク, アキラ
スズキ, タカシ
作成者所属山口大学医学部
内容記述(抄録等)A new human esophageal cancer cell line (YES-2) was established from a surgical specimen obtained from an 81-year-old male potient. This cell line has been maintained for 68 months through 196 passages. YES-2 cells have clear polygonal shaped cytoplasm, round nuclei and prominent nucleoli. The cells proliferate in a pavement-like cell arrangement and show a lack of contract inhibition. The doubling time at the 102nd passage was 23.7 hours. YES-2 cells produce squamous cell carcinoma antigen (SCC antigen), tissue polypeptide antigen (TPA) and carcinoantigen 125 (CA 125) as tumor markers. Chromosome analysis has shown that the chromosome number ranges from 53 to 62 with a mode of 60. Tumorigenicity has been demonstrated by development of tumor after the subcutaneous injection of YES-2 cells into nude mice. These findings indicate that the YES-2 cell line is a new human esophageal cancer cel line which may be useful for various studies.
本文言語eng
著者キーワードFrozen section diagnosis
Flow cytometry
DNA aneuploidy
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
41
3-4
開始ページ149
終了ページ153
発行日1994-12
著者版/出版社版出版社版
リポジトリIDA020041000311
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020041000311