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フルテキストURLA020011000303.pdf ( 1.8MB ) 公開日 2010-04-16
タイトルOn the Role of Calcium Ion in the Contractility of the Frog's Stomach Muscle
作成者Sakata, Yozo
Kawabata, Gorou
作成者ヨミサカタ, ヨウゾウ
カワバタ, ゴロウ
作成者所属山口大学医学部
内容記述(抄録等)1. The isotonis sontrastion (shortening) of the muscle-strip from the pyloric portion of frog's stomach was investigated in the physiological solution, in which the calcium or the potassium cantent was either decreased or increased. 2. When the calcium ion was deprived from the bathing solution, the contractile response to acetylcholine could not be observed after one hour or more. Generally, the preparation relaxed gradually to a full extent in the calcium-free solution. If the bath was changed to that containing the calcium, it shortened again and the responsibility to acetylholine reappeared. 3. The contractile response to acetylcholine or to rlrctric stimulus could be observed with the depolarized muscle in a potassium-rich solution. The shortening of contracture induced by high-potassium was maintained in Ca-containing solution but was not, in Ca-free one. 4. In the contractile response to acetylcholine, two kinds of shortening, a fast component and a slow component, could be distinguished in different proportions. The slow component disappeared much earlier than the fast one in a Ca-free solution. There was no finding to differentiate the former and the maintained shortening or contracture. 5. Concerning the role of calcium ion in the contractile mechanism, it was discussed as a working hypothesis that the entrance of calcium ion from the extracellular fluid or the protoplasmic membrane into the maintained state of shortening would have a relationship with the concentration of calsium existing inside the muscle fibre.
本文言語eng
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
11
3
開始ページ141
終了ページ150
発行日1964-09
著者版/出版社版出版社版
リポジトリIDA020011000303
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020011000303