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フルテキストURLA020028000101.pdf ( 4.1MB ) 公開日 2010-04-19
タイトルPathological Study on Amyloidosis : Localized Deposition of Amylid; Dystrophic or Age-dependent Amyloid
作成者Nakamura, Hidenori
作成者ヨミナカムラ, ヒデノリ
作成者所属山口大学医学部
内容記述(抄録等)The effects of sciatic nerve stimulation on the electroencephalogram (EEG), cerebral metabolic rate for oxygen (CMRo_2) and cerebral blood flow (CBF) were investigated at five different levels of thiopental anesthesia. Thiopental was infused intravenously at the constant rate of 23 mg/kg/hour for 2 hours, and anethetic levels at 10 (plasma concentration of thipental 15±2 μg/mg), 30(27±3), 60(37±6), 90(42±6) and 120 minutes (49±6) after the start of infusion were designated levels I, II, III, IV and V, respectively. With increasing dose of thiopental, the EEG changed from fast wave activeity to irregular slow wave acticity and then burst suppression. These EEG changes were accompanied by the progressive reduction of CMRo_2 and CBF, decreasing to 58 and 59 per cent of the value before thiopental at level V, respectively. The effects of stimulation for 5 minutes were tested at each level. At level I the mean CMRo_2 and CBF increased to 110 and 107 per cent of control, respectively, accompanied by EEG activation. At level II the CMRo_2 and CBF increased at 1 minute to 106 and 107 per cent of control, respectively, accompanied unchanged. These results suggest that tight coupling between the EEG, CMRo_2 and CBF exists during thiopental anesthesia.
本文言語eng
著者キーワードamyloidosis
dystrophic amyloid
aging
β-fibrilloses
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
28
1-2
開始ページ1
終了ページ9
発行日1981-06
著者版/出版社版出版社版
リポジトリIDA020028000101
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020028000101