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タイトルAngio-Immunoblastic Lymphadenopathy (A.I.L)の一症例
タイトルヨミangio-immunoblastic lymphadenopathy (a.I.l) ノ イチ ショウレイ
タイトル別表記A Case of Angio-Immunoblastic Lymphadenopathy
作成者藤本, 繁樹
山時, 好郎
山時, 脩
村上, 通治
水田, 英司
岡, 正朗
松本, 正
奥, 知三
作成者ヨミフジモト, シゲキ
サントキ , ヨシロウ
サントキ, オサム
ムラカミ, ミチハル
ミズタ, エイシ
オカ, マサアキ
マツモト, タダシ
オク, トモゾウ
作成者別表記Hujimoto, Shigeki
Santokii, Yosiro
Santoki, Osamu
Murakami, Michiharu
Mizuta, Eishi
Oka, Masaaki
Matsumoto, Tadashi
Oku, Tomozo
作成者所属山口大学医学部
内容記述(抄録等)A new disease entity of the lymphocyte-plasma cell system characterized by generalised lymphadenop athy, skin rashes, fever, and hypergammaglobulinemia has recently been reported by Frizzera and his colleagues as angio-immunoblastic lymphadenopathy with dysproteinemia (A . I . L .) and by Lukes and Tindle as immunoblastic lymphadenopathy. The lymph nodes are dfffusely involved and show proliferation of immunoblasts, plasma cells, and lymphocytes, and many arborizing small vessels, and amorphous, acidphilc materils are also observed. The onset is frequently sudden and the course stormy and complicated by infections. The commonest immunological abnormality in A . I .L .is a diffuse heterogeneous elevation of one, two, or three immunoglobulins. It is not yet clear whether A . I . L . is an immunological or a neoplastic process, but is possible that it is caused by hyperactivity of the immune system. We have lately seen a 72-year-old man who had generalized lymphadenopathy which on biopsy showed finding similar to A . I. L . Serum protein electrophoresis showed a hypergammaglobulinemia and hypoalubuminemia. Radial immunodiffusion showed elevation of IgG and IgM. He was given combination chemotherapy, including Vincristin, Endoxan, 6-MP, and Predonine and accuired complete remission. In view of the suggested possibility of a malignant evolution of this disease, as in order abnormal immunological precesses, a careful long-term follow up is indicated.
本文言語jpn
主題医学
資料タイプtext
出版者山口大学医学会
出版者ヨミヤマグチ ダイガク イガッカイ
NII資料タイプ学術雑誌論文
査読の有無査読あり
ISSN0513-1731
NCIDAN00243156
学内刊行物(紀要等)山口医学
掲載誌名山口医学
26
2
開始ページ129
終了ページ134
発行日1977-06
著者版/出版社版その他
リポジトリIDB030026000209
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/B030026000209