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フルテキストURLA020042000107.pdf ( 3.0MB ) 公開日 2010-04-19
タイトルA Case with Neutrophil Infiltration into Nevus Cell Nest after Intravenous Administration of Interferon-β
作成者Mogami, Satoshi
Hirota, Toru
Nagai, Ko
Okimura, Hiroshi
Muto, Masahiko
Asagami, Chidori
作成者ヨミモガミ, サトシ
ヒロタ, トオル
ナガイ, コウ
オキムラ, ヒロシ
ムトウ, マサヒコ
アサガミ, チドリ
作成者所属山口大学医学部
内容記述(抄録等)Interferon-β therapy has been widely applied for patients with hapatitis C and with malignant melanoma. Its anti-tumor effects on malignant melanoma are well discussed but few reports on anti-tumor effect of the interferon-β to benign tumors are described. A 63-year-old female received interferon-β therapy(dose=6×10 6 units/day) for hepatitis C and developed erythematous change and pain on her intradermal nevus seen on the right external canthus. Histopathological study revealed that the neutrophilic infiltration was localized only in nevus cell nest. It seems interferon-βworked on nevus cells and led the nevocytes to secrete cytokines such as IL-8. A possibility that there is one pathway on anti-tumor effects related to melanin-prpducing cells, via the neutrophils, is suggested.
本文言語eng
著者キーワードintradermal nevus
interferon
neutrophil
anti-tumor effect
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
42
1-2
開始ページ45
終了ページ47
発行日1995-12
著者版/出版社版出版社版
リポジトリIDA020042000107
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020042000107