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フルテキストURLA020026000307.pdf ( 855.0KB ) 公開日 2010-04-19
タイトルPrimary Reading Epilepsy
作成者Ota, Tamio
Mizuki, Akio
Kawasawa, Syuhei
Nakamura, Yoshitsugu
Yamada, Michio
Samura, Yukiko
Shibata, Jiro
Suizu, Kazuo
作成者ヨミオオタ, タミオ
ミズキ, アキオ
カワサワ, シュウヘイ
ナカムラ, ヨシツグ
ヤマダ, ミチオ
サムラ, ユキコ
シバタ, ジロウ
スイズ, カズオ
作成者所属山口大学医学部
内容記述(抄録等)Phosphorylation of two species of erythrocyte pyruvate kinase (PK, EC 2.7.1.40), PK-R_1 and PK-R_2, was analyzed. The light fraction of younger red cells which has a low PK-R_2/PK-R1 ratio, and the dense fraction of older cells which has a high PK ratio were used as the enzyme source. On phosphorylation in the presence of cyclic AMP, PK of the dense fraction showed a larger amount of ^32P incorporation than that of the light fraction. Most of the radioactivity incorporated was recovered in the L' subunit of PK. The unphosphorylated PK of the dense fraction had a lower affinity for phosphorylated PK of the dense fraction still showed a lower affinity for PEP than that of the light fraction. There results indicate that PK-R_1 and PK-R_2 are controlled by phosphorylation with a decrease of the affinity for PEP. The postsynthetic transformation of PK-R_1 into PK-R_2 is considered as a maturation process or molecular aging of the enzyme which involves protein degradation in erythrocytes.
本文言語eng
著者キーワードreading epilepsy
EGG
CT
psychotic state
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
26
3-4
開始ページ123
終了ページ129
発行日1979-12
著者版/出版社版出版社版
リポジトリIDA020026000307
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020026000307