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フルテキストURLA020015000106.pdf ( 773.7KB ) 公開日 2010-04-16
タイトルEnzymological Studies on the Choroid Plexus Following Bilateral Carotid Ligation
作成者Hatano, Mitsunori
作成者ヨミハタノ, ミツノリ
作成者所属山口大学医学部
内容記述(抄録等)The activities of four enzymes which were thought to be correlating with the production of cerebrospinal fluid, such as alkaline and acid phosphatases, carbonic anhydrase and ATPase were determined biochemically in the choroid plexus as well as the frontal lobe tissue in adult rabbits. The activities of alkaline and acid phosphatases and carbonic anhydrase were transiently enhanced in the choroid plexus after bilateral ligation of the carotid arteries, in spite of consistent decrease of their activities observed in the frontal lobe tissue under such condition. As to the ATPase, both total and Na-K activated ATPase, no significant change was observed in its activity in the choroid plexus, while in the frontal lobe tissue it decreased as similar tendency as the others. Cisternal fluid pressure elevated gradually after the carotid ligation, but arterial and venous blood pressures were little affected by this procedure. Vertebral blood flow rate was measured in doges, in order to estimate the change of blood flow within the choroid plexus under the complete interruption of the carotid blood flow. As a result, the flow rate of the vertebral artery was abruptly increased as double as the normal level following the bilateral carotid ligation. Considering the correlation of examined enzymes with secretory function of the choroid plexus, it is suggested that the reflectoric hyperfunction of the choroid plexus may take place under the cessation of the carotid blood flow for at least a transient period.
本文言語eng
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
15
1
開始ページ71
終了ページ83
発行日1968-03
著者版/出版社版出版社版
リポジトリIDA020015000106
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020015000106