Japanese | English

トップページへ戻る

詳細

   
フルテキストURLフルテキストリンクなし
タイトルScanning and transmission electron microscopy of biodegradable microspheres (DSM) in blood vessels
作成者Makita, T.
Ichimal, H.
Kagabu, S.
Manba, K.
Naito, I.
Lindblom, R.
Hatsuoka, M.
Okawa, T.
作成者ヨミカガブ, サトシ
作成者別表記利部, 聰
Kagabu, Satoshi
作成者所属山口大学農学部
内容記述(抄録等)A type of biodegradable microsphere (DSM), approximately 45 um in diameter, made of polymerized potato starch (Pharmacia, Sweden) was intravenously injected into rats to observe the state of DSM in small blood vessels in the kidney and liver at the electron microscopic level. Prior to their digestion with amylase, individual DSM changed their round shape to an irregularly folded one to occupy almost the whole area of the lumen. At the transmission electron microscopic level, DSM were impregnated with colloidal iron and were easily identified. Interaction of the iron labelled DSM with the surface of endothelial cells was unexpectedly loose and no adherence or fusion of this surface was observed. The starch substance was not visible in the pinocytotic vesicles of the endothelium. These findings suggest the independent profile of DSM in situ.
本文言語eng
資料タイプtext
出版者Elsevier
NII資料タイプ学術雑誌論文
査読の有無査読あり
ISSN0309-1651
NCIDAA00600025
掲載誌名Cell biology international reports
13
5
開始ページ427
終了ページ436
発行日1989-05
DOIinfo:doi/10.1016/0309-1651(89)90137-9
関連情報URL(IsPartOf)http://www.sciencedirect.com/science/journal/03091651
著者版/出版社版その他
リポジトリID2008010050
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/2008010050