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タイトルラットおよびイヌにおけるDL-エチオニン投与後の血清GOT,GPT活性並びにビリルビン値の動態
タイトルヨミラット オヨビ イヌ ニオケル DL エチオニン トウヨゴ ノ ケッセイ GOT GPT カッセイ ナラビニ ビニルビン チ ノ ドウタイ
タイトル別表記Changes of Serum GOT, GPT and Bilirubin Values after the Administration of DL-Ethionine in Rats and Dogs
作成者柴田, 浩
谷口, 和彦
作成者ヨミシバタ, ヒロシ
タニグチ, カズヒコ
作成者別表記Shibata, Hiroshi
Taniguchi, Kazuhiko
作成者所属山口大学農学部
内容記述(抄録等)Changes of Serum transaminase (GOT, GPT) and bilirubin values after a single oral or intraperitoneal administration of DL-ethionine (EthN) were studied in rats and dogs. After the administration of EthN, serum transaminase and bilirubin values increased with the increase in dose of EthN in both rats and dogs; however, the degree of increase in these parameters was higher in dogs than in rats. The degree of increase in serum parameters after EthN treatment in rats was similar in both oral and intraperitoneal administration, but the degree of these increase in dogs was higher in intraperitoneal than in oral administration. After the administration of EthN, serum transaminase and bilirubin values increased with the passage of post-administrative time in both rats and dogs; however, the time when these parameters reached the highest value was earlier in rats than in dogs. The rise and fall of the serum parameters after EthN treatment in rats or dogs were similar in both oral and intraperitoneal administration. These differences in response to EthN between rats and dogs may be explained on the basis of different rate of transformation of EthN.
本文言語jpn
著者キーワードDL-ethionine
serum GOT
serum GPT
serum bilirubin
rat
dog
主題農学
資料タイプtext
出版者山口大学農学部
出版者ヨミヤマグチ ダイガク ノウガクブ
NII資料タイプ紀要論文
ISSN0513-1715
NCIDAN00244250
学内刊行物(紀要等)山口大学農学部学術報告
掲載誌名山口大学農学部学術報告
掲載誌名別表記Bulletin of the Faculty of Agriculture, Yamaguchi University
38
開始ページ13
終了ページ23
発行日1990
著者版/出版社版その他
リポジトリIDD490038000002
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/D490038000002