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フルテキストURLA020015000203.pdf ( 1.5MB ) 公開日 2010-04-16
タイトルStudies of Rubella Virus
作成者Konishi, Shunzo
Nohara, Kiyoaki
作成者ヨミコニシ, シュンゾウ
ノハラ, キヨアキ
作成者所属山口大学医学部
内容記述(抄録等)During the rubella epidemic of 1966-1967 in Yamaguchi, one hundred and twenty-seven patints with rubella were studied virologically and seroimmunologically, and the following results were obtained : (1) Concerning the isolation of rubella virus, the direct method using primary rabbit embryo cells was investigated and compared with the indirect method using African green monkey kidney cells and it was found that RE cells were almost the same as GMK cells for susceptibility to rubella virus, that RE cells showed simple cytopathic changes which could be observed directly, and they were very simple to obtain and to manage so that they are well suited for studies of rubella virus. (2) From l27 patients, 48 strains (37.2 %) of rubella virus were isolated by the indirect method using GMK cells and 46 strains (36.2 %) were isolated by the direct method using RE cells. (3) From 6 patients with rubella encephalitis, two strains of rubella virus from throat swabs and one strain from cerebrospinal fluid were isolated. (4) From a fetus, after artificial abortion, of a mother who had had rubella at an early stage of pregnancy, rubella virus was isolated suggesting the possibility of a congenital rubella syndrome. (5) Fifty-four cases (87.0 %) out of 62 cases of rubella patients, pair sera were obtained, showed neutralizing antibody titer rising more than 4-fold. (6)The antibody response of 126cases of pregnant women to rubella virus was examined and found to be under 4-fold in 19 cases (15.1 %) and above 4-fold in 107 cases (84.9%).
本文言語eng
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
15
2
開始ページ99
終了ページ112
発行日1968-06
著者版/出版社版出版社版
リポジトリIDA020015000203
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020015000203