Japanese | English

トップページへ戻る

詳細

   
フルテキストURLA050054000101.pdf ( 792.6KB ) 公開日 2010-04-19
タイトルThymic architectures for T cell production and structural and functional recovery from their radiation injuries
作成者Fukumoto, Tetsuo
Adachi, Yasuhiro
Tokuda, Nobuko
Sawada, Tomoo
Arudchelvan, Yamini
作成者ヨミフクモト, テツオ
アダチ, ヤスヒロ
トクダ, ノブコ
サワダ, トモオ
作成者別表記安達, 泰弘
徳田, 信子
澤田, 知夫
作成者所属山口大学医学部
内容記述(抄録等)The thymus is an important organ for producing T cells. Thymic structures consist of thymic epithelial cells among which thymocytes proliferate and maturate. The structural and functional recovery of the rat thymus after irradiation was studied morphologically and by the message expression changes of several cytokines. In this manuscript we tried to describe further details of rat thymic epithelial cells in respect to therir electron microscopic features as well as their function to interact with thymocytes. Then the mechanisms responsible for the regeneration of the thymus after irradiation were considered. Not only the reproliferation of the thymocytes but also the regeneration of the vasculatures and thymic epithelial cells are considered important for thymus regeneration. Cytokine message changes were shown to be seriously involved for the degree of recovery of the thymus tissue after irradiation.
本文言語eng
著者キーワードthymus
thymic epithelial cells
irradiation
regeneration
cytokines
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University School of Medicine
NII資料タイプ紀要論文
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
54
1-2
開始ページ1
終了ページ7
発行日2007
関連情報URL(IsPartOf)http://ds.cc.yamaguchi-u.ac.jp/~bulletin/index.html
著者版/出版社版出版社版
リポジトリIDA050054000101
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A050054000101