| フルテキストURL | A050054000101.pdf ( 792.6KB ) 公開日 2010-04-19
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| タイトル | Thymic architectures for T cell production and structural and functional recovery from their radiation injuries |
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| 作成者 | Fukumoto, Tetsuo
Adachi, Yasuhiro
Tokuda, Nobuko
Sawada, Tomoo
Arudchelvan, Yamini
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| 作成者ヨミ | フクモト, テツオ
アダチ, ヤスヒロ
トクダ, ノブコ
サワダ, トモオ
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| 作成者別表記 | 安達, 泰弘
徳田, 信子
澤田, 知夫
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| 作成者所属 | 山口大学医学部
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| 内容記述（抄録等） | The thymus is an important organ for producing T cells. Thymic structures consist of thymic epithelial cells among which thymocytes proliferate and maturate. The structural and functional recovery of the rat thymus after irradiation was studied morphologically and by the message expression changes of several cytokines. In this manuscript we tried to describe further details of rat thymic epithelial cells in respect to therir electron microscopic features as well as their function to interact with thymocytes. Then the mechanisms responsible for the regeneration of the thymus after irradiation were considered. Not only the reproliferation of the thymocytes but also the regeneration of the vasculatures and thymic epithelial cells are considered important for thymus regeneration. Cytokine message changes were shown to be seriously involved for the degree of recovery of the thymus tissue after irradiation.
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| 本文言語 | eng
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| 著者キーワード | thymus
thymic epithelial cells
irradiation
regeneration
cytokines
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| 主題 | 医学
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| 資料タイプ | text |
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| ファイル形式 | application/pdf |
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| 出版者 | Yamaguchi University School of Medicine
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| NII資料タイプ | 紀要論文 |
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| 学内刊行物(紀要等) | The bulletin of the Yamaguchi Medical School |
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| 掲載誌名 | The bulletin of the Yamaguchi Medical School |
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| 巻 | 54 |
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| 号 | 1-2 |
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| 開始ページ | 1 |
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| 終了ページ | 7 |
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| 発行日 | 2007 |
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| 関連情報URL(IsPartOf) | http://ds.cc.yamaguchi-u.ac.jp/~bulletin/index.html
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| 著者版/出版社版 | 出版社版 |
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| リポジトリID | A050054000101 |
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| 地域区分 | 山口大学
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| URI | http://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A050054000101 |
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