| フルテキストURL | A020037000104.pdf ( 2.0MB ) 公開日 2010-04-19
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| タイトル | The Measurement of Brainstem Blood Flow in the Experimental Recirculation Model of Brainstem Ischemia in the Rat |
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| 作成者 | Shiroyama, Yujiro
Nagamitsu, Tsutomu
Yamashita, Tetsuo
Abiko, Seisho
Ito, Haruhide
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| 作成者ヨミ | シロヤマ, ユウジロウ
ナガミツ, ツトム
ヤマシタ, テツオ
アビコ, セイショウ
イトウ, ハルヒデ
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| 作成者所属 | 山口大学医学部
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| 内容記述（抄録等） | This report describes a surgical approach and measurement of brainstem blood flow (BBF) used in experimental ischemic model of the brainstem. The vertebral artery of Wistar rat was exposed and prepared embolic thread was inserted into the vertebral artery. The lesions of the baselar artery occuleded animals were restricted to the brainstem which, in the rat, is normally supplied by the vertebrobasilar artery. Using the hydrogen clearance techniques, blood flow of the brainstem was measured in 21 rats. The mean value of mean blood pressure (MBP) was 96.2±6.2 mmHg before ischemia. It dropped to 62.0±12.4 mmHg after transient hypertension. The preischemic BBF was 35.5±2.4 ml/100g/min. This was followed by a gradual increase to hyperperfusion after recirculation. After 1 hour of recirculation, BBF rose to a level above 78.9±5.9 ml/100g/min. These findings suggest that this model may be useful in the evaluation of pathophysiogical changes in brainstem ischemia.
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| 本文言語 | eng
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| 著者キーワード | Brainstem
Ischemia
Recirculation
Hyperperfusion
Vasomotor center
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| 主題 | 医学
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| 資料タイプ | text |
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| ファイル形式 | application/pdf |
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| 出版者 | Yamaguchi University Graduate School of Medicine
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| NII資料タイプ | 紀要論文 |
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| ISSN | 0513-1812
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| NCID | AA00594272
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| 学内刊行物(紀要等) | The bulletin of the Yamaguchi Medical School |
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| 掲載誌名 | The bulletin of the Yamaguchi Medical School |
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| 掲載誌名別表記 | 山口医科大学紀要 |
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| 巻 | 37 |
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| 号 | 1-2 |
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| 開始ページ | 25 |
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| 終了ページ | 30 |
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| 発行日 | 1990-06 |
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| 著者版/出版社版 | 出版社版 |
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| リポジトリID | A020037000104 |
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| 地域区分 | 山口大学
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| URI | http://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020037000104 |
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