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フルテキストURLA020016000210.pdf ( 2.4MB ) 公開日 2010-04-16
タイトルStudies on the Production of the Complement Fixing Factor in Reaction to Autologous Liver Tissue
作成者Nishioka, Mikio
Ibata, Takayoshi
Miyazato, Kaoru
Fujita, Teruo
作成者ヨミニシオカ, ミキオ
イバタ, タカヨシ
ミヤザト, カオル
フジタ, テルオ
作成者所属山口大学医学部
内容記述(抄録等)Hepatic proteins were demonstrated in the sera of rats given thioacetamide. These hepatic proteins remained in the blood for 3 to 4 days. At such times, when hepatic proteins had disappeared from the blood, complement fixing factors reacting with the saline extracts of both autologous and homologous rat livers were found in the sera from the rats, and disappeared by the tenth day. In rats which had been given weekly injections of thioacetamide for a month and this followed by a maintenance injection, it was found that complement fixing factor appeared sporadically in low titer. Complement axing factor may be related to IgM. After the thioacetamide injection severe hepatic necrosis and fibrosis were found in all rats, but this damage was completely repaired within 2 months except for a slight fatty infiltration. Complement fixing autoantibodies may be an immunological response to the hepatic proteins which were released following acute hepatic damage.
本文言語eng
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
16
2-4
開始ページ195
終了ページ204
発行日1969-12
著者版/出版社版出版社版
リポジトリIDA020016000210
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020016000210