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フルテキストURLA020016000208.pdf ( 914.0KB ) 公開日 2010-04-16
タイトルSignificance of Zinc Metabolism in Blood Granulocytes in Surgical Cancer Patients
作成者Fuchimoto, Takeshi
Takashima, Masanari
Fujii, Masataka
Santoki, Yoshiro
Shirozu, Hideharu
Santoki, Osamu
作成者ヨミフチモト, タケシ
タカシマ, マサナリ
フジイ, マサタカ
サントキ, ヨシロウ
シロズ, ヒデハル
サントキ, オサム
作成者所属山口大学医学部
内容記述(抄録等) Significance of zinc metabolism in blood granulocytes was studied in surgical cancer patients. The zinc content of blood granulocytes was analyzed using the histochemical method of McNary and the score method of Szmigielski and Litwin. The zinc score in preoperative cancer patients was markedly lower than that in non-cancer patients. This low values were not observed in most of early carcinomas while the score was almost always lowered in non-resectable carcinomas. This suggests that zinc metabolism in blood granulocytes is not disturbed until cancer progresses beyond a certain extent. The low score in preoperative cancer patients was elevated to normal values 3 to 5 weeks after the curative operation with or without cancer chemotherapy. In non-resectable carcinomas, changes in the zinc score following cancer chemotherapy seemed to run parallel with its effectiveness. These observations indicate that there is a close relation between the zinc content of blood granulocytes and the progress of cancer. This histochemical method is useful as a clinical routine method to examine the progress of cancer.
本文言語eng
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
16
2-4
開始ページ173
終了ページ182
発行日1969-12
著者版/出版社版出版社版
リポジトリIDA020016000208
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020016000208